Document Details

Document Type : Article In Journal 
Document Title :
DARPins Bioengineering and its Theranostic Approaches: Emerging Trends in Protein Engineering.
DARPins Bioengineering and its Theranostic Approaches: Emerging Trends in Protein Engineering.
Document Language : English 
Abstract : The therapeutic significance of bioengineering proteins has increased dramatically as a new generation of pharmacological drug with a great potential in medical treatment. Protein engineering has improved the use of new non immunoglobulin affinity proteins. The designed ankyrin repeat proteins abbreviated as DARPins is a classical example. These molecules have smaller structural size, unlike immunoglobulins, but similar target affinity is of great significance. Such molecules get more binding specificity and greater thermodynamic stability. These attributes made DARPins a favorite player in diagnostics and therapeutics of cancer. How DARPins are improved into vigorous and versatile scaffold for binding protein and selected by ribosome and phage display along with related aspects is discussed in this review. 
ISSN : 1381-6128 
Journal Name : Current pharmaceutical design 
Volume : 23 
Issue Number : 11 
Publishing Year : 1437 AH
2016 AD
Article Type : Article 
Added Date : Tuesday, July 18, 2017 


Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
M. RasoolRasool, M. ResearcherDoctorate 
A. MalikMalik, A. ResearcherDoctorate 
M HussainHussain, M ResearcherDoctorate 
KA HaqHaq, KA ResearcherDoctorate 
K ButtButt, K ResearcherDoctorate 
MAB AshrafAshraf, MAB ResearcherDoctorate 
MI NaseerNaseer, MI ResearcherDoctorate 
M AsifAsif, M ResearcherDoctorate 
R ShaikhShaikh, R ResearcherDoctorate 
MZ MustafaMustafa, MZ ResearcherDoctorate 
Q AlamAlam, Q ResearcherDoctorate 
G RasoolRasool, G ResearcherDoctorate 
W AhmadAhmad, W ResearcherDoctorate 
A HaqueHaque, A ResearcherDoctorate 
MA KamalKamal, MA ResearcherDoctorate 


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