Genomic Screening Research Program
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 The Genetic Screening Research Program (GSRP) currently encapsulates two active research groups that focus on studying the molecular genetic causes of two common afflictions affecting the Saudi population: Deafness and Thrombophilia. The GSRP is a multi-disciplinary research program with a great potential of continuous expansion.
One of the major areas of expansion in this program is the Preimplantation Genetic Diagnosis (PGD), which is considered as a very early form of prenatal diagnosis. PGD is an adjunct to assisted reproductive technology since, it can lead to avoiding selective pregnancy termination, and PGD requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation.
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Goals:
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Identification of the molecular causes of genetic diseases predominant in the Kingdom of Saudi Arabia and establishing a relevant set of biomarkers that can aid in the diagnosis, prognosis or treatment. |
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Introduce state-of-the art technology such as pyrosequencing, dHPLC, microarrays for mutation and subsequent gene expression analysis. |
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Establish PGD service for various genetic abnormalities such as: sickle cell hemophilia, thalassemia, huntington’s chorea, DMD, Cystic Fibrosis and metabolic disorder screening. |
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Explore PGD applications in complex yet common traits such as adult onset diabetes, familial CHD, and certain familial cancers. |
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Possibly augment PGD and stem cell therapy as a therapeutic intervention. |
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Genomic Screening Research Group:
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