Document Details

Document Type : Article In Journal 
Document Title :
STRait Razor v2.0: the improved STR Allele Identification Tool--Razor
STRait Razor v2.0: the improved STR Allele Identification Tool--Razor
 
Document Language : English 
Abstract : STRait Razor (the STR Allele Identification Tool - Razor) was developed as a bioinformatic software tool to detect short tandem repeat (STR) alleles in massively parallel sequencing (MPS) raw data. The method of detection used by STRait Razor allows it to make reliable allele calls for all STR types in a manner that is similar to that of capillary electrophoresis. STRait Razor v2.0 incorporates several new features and improvements upon the original software, such as a larger default locus configuration file that increases the number of detectable loci (now including X-chromosome STRs and Amelogenin), an enhanced custom locus list generator, a novel output sorting method that highlights unique sequences for intra-repeat variation detection, and a genotyping tool that emulates traditional electropherogram data. Users also now have the option to choose whether the program detects autosomal, X-chromosome, Y-chromosome, or all STRs. Concordance testing was performed, and allele calls produced by STRait Razor v2.0 were completely consistent with those made by the original software. 
ISSN : 1878-0326 
Journal Name : Forensic Sci Int Genet 
Volume : 14 
Issue Number : 1 
Publishing Year : 1436 AH
2015 AD 
Article Type : Article 
Added Date : Sunday, May 1, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
David H. WarshauerWarshauer, David H.Investigator  
Jonathan L. KingKing, Jonathan L.Researcher  
Bruce BudowleBudowle, Bruce Researcher Bruce.Budowle@unthsc.edu

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