Document Details

Document Type : Article In Journal 
Document Title :
Gestational Influenza Increases the Risk of Psychosis in Adults
Gestational Influenza Increases the Risk of Psychosis in Adults
 
Document Language : English 
Abstract : Psychotic disorders are complex and caused by interplay of genetic and environmental factors. Influenza is a common infectious disease in humans, and it has been suggested that maternal influenza is an estimated risk factor for psychotic disorders, especially for schizophrenia. In view of conflicting results of this association in literature, we performed the strict meta-analysis to examine whether maternal influenza is a risk factor for psychosis in the children. Four ecological studies and three birth cohort studies were included in our meta-analysis. It has been observed that the Risk Ratio (RR) of maternal influenza on psychosis is 1.062 (95% Confidence Interval (CI) = 1.004-1.123) for the analysis of ecological studies and the RR is 1.564(95%CI=1.051-2.324) for the analysis of birth cohort studies. Furthermore, a survey of pregnant women and fetus' health in Nanjing of China indicated that only 1.5% of women received the influenza vaccine before pregnancy, 0.4% received it during pregnancy, and 5.1% were willing to receive the influenza vaccine if necessary. These results showed that gestational influenza could increase mental disorders risks in adult offspring besides its established harms for gravidas. Results suggest it might be effective to increase attention to gravidas to protect them from influenza infection through encouragement of vaccinations. 
ISSN : 0144-929X 
Journal Name : Medicinal Chemistry 
Volume : 11 
Issue Number : 7 
Publishing Year : 1436 AH
2015 AD 
Article Type : Article 
Added Date : Monday, April 18, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
Lei CaiCai, Lei Investigator lcai@gordonlifescience.org
Chun-Lin WanWan, Chun-Lin Researcher  
Lin HeHe, Lin Researcher  
Simone de JongJong, Simone deResearcher  
Kuo-Chen ChouChou, Kuo-Chen Researcher  

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