Document Details

Document Type : Article In Journal 
Document Title :
Alzheimer's and type 2 diabetes treatment via common enzyme targeting.
Alzheimer's and type 2 diabetes treatment via common enzyme targeting.
 
Document Language : English 
Abstract : Alzheimer's disease (AD) and type 2 diabetes mellitus (T2DM) are two devastating diseases that are currently incurable. Epidemiological, clinical and pathological evidence has confirmed the co-existence of these two disorders. Moreover, there has been promising progress made in the identification of the pathological linkage between T2DM and AD in the last decade. Hence, developing common treatment strategies for these diseases is important. Currently, enzyme targeting is a potential strategy to cure many diseases. In this communication, we tried to summarize the single enzymetargeted therapeutic approach for the treatment of AD and T2DM. This field of research continues to be active and progressive in identifying many promising enzymes that are involved in both diseases. Based on this review article, we also believe that enzyme inhibition is a promising and reliable strategy for the treatment of many incurable diseases. In the future, we expect that the scientific community will be able to develop common enzyme inhibitors for the treatment of both AD and T2DM. 
ISSN : 1871-5273 
Journal Name : CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS & Neurological Disorder 
Volume : 13 
Issue Number : 2 
Publishing Year : 1434 AH
2013 AD 
Article Type : Article 
Added Date : Tuesday, April 5, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
Nasimudeen R JabirR Jabir, Nasimudeen Researcher  
Mohammad A KamalA Kamal, Mohammad Researcher  
Adel Mohammad AbuzenadahMohammad Abuzenadah, Adel Researcher  
Siew Hua GanHua Gan, Siew Researcher  
Mohammed Nabil AlamaNabil Alama, Mohammed Researcher  
Saleh S BaeesaS Baeesa, Saleh Researcher  
Shams TabrezTabrez, Shams Investigator  

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