Document Details
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Document Type |
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Article In Journal |
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Document Title |
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Developmental validation of the EX20+4 system Developmental validation of the EX20+4 system |
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Document Language |
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English |
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Abstract |
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The EX20+4Y System is a polymerase chain reaction (PCR)-based amplification kit that enables typing of
19 autosomal short tandem repeat (STR) loci (i.e., CSF1PO, D13S317, D16S539, D18S51, D21S11,
D3S1358, D5S818, D7S820, D8S1179, FGA, TH01, TPOX, vWA, Penta D, Penta E, D2S1338, D19S433,
D12S391, D6S1043), four widely used Y chromosome-specific STR (Y-STR) loci (DYS458, DYS456,
DYS391, DYS635), and amelogenin. In this study, this multiplex system was validated for sensitivity of
detection, DNA mixtures, inhibitor tolerance, species specificity based on the Scientific Working Group
on DNA Analysis methods (SWGDAM) developmental validation guidelines, and the Chinese criteria for
the human fluorescent STR multiplex PCR reagent. The results show that the EX20+4 System is a robust
and reliable amplification kit which can be used for human identification testing. |
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ISSN |
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1872-4973 |
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Journal Name |
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Forensic Science International: Genetics |
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Volume |
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11 |
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Issue Number |
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1 |
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Publishing Year |
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1435 AH
2014 AD |
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Article Type |
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Article |
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Added Date |
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Monday, March 21, 2016 |
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Researchers
| Shuanglin Li | Li, Shuanglin | Investigator | | |
| Changhui Liu | Liu, Changhui | Researcher | | |
| Chao Liu | Liu, Chao | Researcher | | |
| Hong Liu | Liu, Hong | Researcher | | |
| Jianye Ge | Ge, Jianye | Researcher | | |
| Bruce Budowle | Budowle, Bruce | Researcher | | |
| Weiguo Zheng | Zheng, Weiguo | Researcher | | |
| Fayuan Li | Li, Fayuan | Researcher | | |
| Binwen Ge | Ge, Binwen | Researcher | | |
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