Document Details

Document Type : Article In Journal 
Document Title :
Cancer chemoprevention by polyphenols and their potential application as nanomedicine
Cancer chemoprevention by polyphenols and their potential application as nanomedicine
 
Document Language : English 
Abstract : Today cancer is a leading cause of death among the developed countries. Its highly complex nature makes it difficult to understand as it entails multiple cellular physiological systems such as cell signaling and apoptosis. The biggest challenges faced by cancer chemoprevention/chemotherapy is maintaining drug circulation and avoiding multidrug resistance. Overall there is modest evidence regarding the protective effects of nutrients from supplements against a number of cancers. Numerous scientific literatures available advocate the use of polyphenols for chemoprevention. Some groups have also suggested use of combination of nutrients in cancer prevention. However, we have yet to obtain the desired results in the line of cancer chemotherapy research. Nanotechnology can play a pivotal role in cancer treatment and prevention. Moreover, nanoparticles can be modified in various ways to prolong circulation, enhance drug localization, increase drug efficacy, and potentially decrease the chances of multidrug resistance. In this communication, we will cover the use of various polyphenols and nutrients in cancer chemoprevention. The application of nanotechnology in this regard will also be included. In view of available reports on the potential of nanoparticles, we suggest their usage along with different combination of nutrients as cancer chemotherapeutic agents. 
ISSN : 1059-0501 
Journal Name : Journal of Environmental Science and Health, Part C 
Volume : 31 
Issue Number : 1 
Publishing Year : 1434 AH
2013 AD 
Article Type : Article 
Added Date : Tuesday, March 8, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
Shams TabrezTabrez, Shams Investigator  
Medha PriyadarshiniPriyadarshini, Medha Researcher  
Maryam UroojUrooj, Maryam Researcher  
Shazi ShakilShakil, Shazi Researcher  
Ghulam Md AshrafAshraf, Ghulam Md Researcher  
Mohd Shahnawaz KhanKhan, Mohd Shahnawaz Researcher  
Mohammad Amjad KamalKamal, Mohammad Amjad Researcher  
Qamre AlamAlam, Qamre Researcher  
Nasimudeen R JabirJabir, Nasimudeen R Researcher  
Adel Mohammad AbuzenadahAbuzenadah, Adel Mohammad Researcher  

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