Document Details
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Document Type |
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Article In Journal |
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Document Title |
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A prospective study of congenital malformations amonglive born neonates at a University Hospital in Western Saudi Arabia A prospective study of congenital malformations amonglive born neonates at a University Hospital in Western Saudi Arabia |
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Document Language |
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English |
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Abstract |
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Objective: To estimate the incidence of major and minor
congenital malformations among liveborn infants at King
Abdulaziz University Hospital, Jeddah, Saudi Arabia. Estimation
of risk factors were also evaluated.
Methods: Between March 2004 and May 2005, a total of 5356
babies born at King Abdulaziz University Hospital, were enrolled
in this study for malformations. Details of cases were recorded
after parents’ interviews, clinical, radiological, and laboratory
evaluations.
Results: One hundred and forty-seven (27.06/1000 livebirth)
and 13 (2.39/1000 birth) stillbirth had congenital anomalies.
In all livebirth, incidences of major anomalies were 93.9%
and minor were 6.1%. Mothers of 95.9% with congenital
malformation were healthy, 3.4% were diabetic and 0.7%
had cardiac malfomation. In 38.8% of cases parents were
consanguineous. Among the liveborn births, the most common
system involved was cardiovascular (7.1/1000), followed by
musculoskeletal/limb (4.1/1000), external genitalia (2.8/1000),
urinary (2.6/1000), multiple chromosomal (2.2/1000), orofacial
(1.9/1000), central nervous system (1.9/1000), skin (1.7/1000),
multiple single gene (1.3/1000), multiple sequence (0.75/1000), eyes
(0.56/1000), unclassified (0.19/1000), musculoskeletal/abdominal
(0.19/1000), endocrine (0.19/1000).
Conclusion: High incidence of major malformation in Jeddah.
Importance of Genetic Counseling is revealed in our study since
more than three quarters of mothers were under 36 years, and
may well plan future pregnancies. |
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ISSN |
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0379-5284 |
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Journal Name |
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Saudi Med J |
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Volume |
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28 |
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Issue Number |
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9 |
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Publishing Year |
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1426 AH
2007 AD |
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Article Type |
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Article |
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Added Date |
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Tuesday, April 27, 2010 |
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Researchers
| نادية فدا | M. Fida, Nadia | Investigator | Doctorate | nadiafida@hotmail.com |
| محمد القحطاني | Al-Qahtani, Mohammed | Researcher | Doctorate | |
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