Document Details

Document Type : Article In Journal 
Document Title :
Kinesin superfamily proteins (KIFs): Various functions and their relevance for important phenomena in life and diseases
Kinesin superfamily proteins (KIFs): Various functions and their relevance for important phenomena in life and diseases
 
Document Language : English 
Abstract : Kinesin superfamily proteins (KIFs) largely serve as molecular motors on the microtubule system and transport various cellular proteins, macromolecules, and organelles. These transports are fundamental to cellular logistics, and at times, they directly modulate signal transduction by altering the semantics of informational molecules. In this review, we will summarize recent approaches to the regulation of the transport destinations and to the physiological relevance of the role of these proteins in neuroscience, ciliary functions, and metabolic diseases. Understanding these burning questions will be essential in establishing a new paradigm of cellular functions and disease pathogenesis. 
ISSN : 1090-2422 
Journal Name : Exp Cell Res 
Volume : 334 
Issue Number : 1 
Publishing Year : 1436 AH
2015 AD 
Article Type : Article 
Added Date : Wednesday, April 20, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
Nobutaka HirokawaHirokawa, Nobutaka Investigator hirokawa@m.u-tokyo.ac.jp
Yosuke TanakaTanaka, Yosuke Researcher  

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