Center of Excellence In Genomic Medicine Research | Researches | Morphologically distinct phenotypes of spermatozoa in infertile men reveal down regulation of multiple signaling pathways

Center of Excellence In Genomic Medicine Research

Document Details

Document Type	:	Article In Journal
Document Title	:	Morphologically distinct phenotypes of spermatozoa in infertile men reveal down regulation of multiple signaling pathways Morphologically distinct phenotypes of spermatozoa in infertile men reveal down regulation of multiple signaling pathways
Document Language	:	English
Abstract	:	Seven morphologically distinct spermatozoal phenotypes can be detected in human semen under electron microscopy: sperm with dysplasia of the fibrous sheath, non-specific flagellar defects, immotile cilia syndrome, acrosomal hypoplasia, defective chromatin condensation and compaction, pin head and sperm without heads. These conditions cannot be identified by routine semen analysis because they are but secondary manifestations of underlying pathology. We hypothesize that proteomics would enable us to better understand the mechanism(s) underlying these pathologies.
ISSN	:	0015-0282
Journal Name	:	Fertility and Sterility
Volume	:	104
Issue Number	:	3
Publishing Year	:	1436 AH 2015 AD
Article Type	:	Article
Added Date	:	Tuesday, April 5, 2016

Researchers

Researcher Name (Arabic)	Researcher Name (English)	Researcher Type	Dr Grade	Email
A Agarwal	Agarwal, A	Investigator
Z Cui	Cui, Z	Researcher
R Sharma	Sharma, R	Researcher
L Samanta	Samanta, L	Researcher
R Turki	Turki, R	Researcher
M Abu-Elmagd	Abu-Elmagd, M	Researcher

Files

File Name	Type	Description
38448.pdf	pdf

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