Document Details

Document Type : Article In Journal 
Document Title :
Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis
Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis
 
Document Language : English 
Abstract : There are a number of pharmacological agents for the treatment of bone mineral loss and osteoporosis. Hormone replacement therapy (HRT) with estrogen is an established treatment, but it has several adverse side effects and can increase the risk of cancer, heart disease, and stroke. There is increasing interest in nutritional factors and naturally occurring phytochemical compounds with the potential for preventing age-related and postmenopausal bone loss. Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a polyphenolic phytoestrogen with osteogenic and osteoinductive properties. It can modify the metabolism of bone cells and has the capacity to modulate bone turnover. This paper provides an overview of current research on resveratrol and its effects on bone cells in vitro, highlighting the challenges and opportunities facing this area of research, especially in the context of providing nutritional support for postmenopausal women who may not benefit from HRT and older patients with various forms of arthritis, metabolic bone disease, and osteoporosis. 
ISSN : 1749-6632 
Journal Name : Annals of the New York Academy of Sciences 
Volume : 1290 
Issue Number : 1 
Publishing Year : 1434 AH
2013 AD 
Article Type : Article 
Added Date : Tuesday, March 15, 2016 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
Ali MobasheriMobasheri, Ali Investigator  
Mehdi ShakibaeiShakibaei, Mehdi Researcher  

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