Dr. Syed Kashif Zaidi

Home >> Research Staff >> Syed Kashif Zaidi - Ph.D
Assistant Professor 
Assistant of Tissue Culture Service Unit
Pharmacogenomics and Tissue Culture & Regenerative Medicine Research Groups

Dr. Syed Kashif Zaidi, as Assistant Professor and involved in tissue culture unit in Center of Excellence in Genomic Medicine Research (CEGMR), King Abdulaziz University since Nov, 2012 is using cutting edge molecular biology techniques to understand the signaling pathways involved in aging process. His fascinating work is geared towards creating new animal models to better understand the process involved in aging. Dr. Zaidi received his Ph.D. in 2005 from the Department of Biochemistry, Aligarh Muslim University, INDIA. During his research work, he was involved in observing the preventive and prophylactic effects of antioxidant compounds in restraint stress induced animal models.
His work on aging began while he was a postdoctoral fellow at Department of Endocrinology, Stanford University (California), where he worked on cholesterol transporter protein (StAR) and had established the significance of this receptor protein in mediating the cholesterol transport to mitochondria and regulation of steroidogenesis during aging.
Dr. Zaidi’s breakthrough was supported by a prestigious funding agency King Abdulaziz City for Science and Technology (KACST), through funding two big grants worth 4 million Saudi Riyals as Principal Investigator

Selected Publications:
1. P38 MAPK regulates steroidogenesis through transcriptional repression of steroidogenic acute regulatory (StAR) protein gene.
Syed Kashif Zaidi, Wen-Jun Shen, Stefanie Bittner, Mark P McLean, Jiahuai Han, Roger J Davis, Fredric B Kraemer and Salman Azhar.
J Mol Endocrinol. 2014.

2. Protective effect of Solanum nigrum aqueous leaf extract on immobilization stress induced changes in rat brain.
Syed Kashif Zaidi, MN. Hoda, SA. Ansari, MA Jaffrey, Naheed Banu, MH. Alqahtani.
Evid Based Complement Alternat Med. 2014.

3. Remote Ischemic Preconditioning is effective after embolic stroke in overiectomized female mice.
M. Hoda, K. Bhatia, S. Hafez, MH. Johnson, S. Siddiqui. Syed Kashif Zaidi, A. Ergul, SC. Fagan, Davis C Hess.
Transl Stroke Res. 2014.

4. Ablation of Vimentin Results in defective steroidogenesis.
Wen-Jun Shen, Syed Kashif Zaidi, Shailja Patel, Yuan Cortez, Masami Ueno, Rakia Azhar, Salman Azhar, Fredrick B. Kraemer.
Endocrinology, 2012.

5. Persistant expression of hepatitis C virus on structural proteins leads to increased autophagy and mitochondrial injury in human hepatoma cells.
Victor Chu, Sayanti Bhattacharya, Ann Nomoto, Syed Kashif Zaidi,, Jiahui Lin, Terry Oberly, Steven Weinman, Salman Azhar and Ting-Ting Huang.
PLoS One. 2011.
Dr. Syed Kashif Zaidi

Last Update
2/15/2015 11:22:03 AM