|Prof. Muhammad Abu-Elmagd
Head of the Functional and Developmental Genomics Unit
Developmental, Reproductive and Cancer Genomics Research Groups
Coordinator of the Teratogenicity, Toxicity and Proteomics Service Units
Prof. Abu-Elmagd obtained his undergraduate degree and M.Sc. from Department of Zoology, Faculty of Science, Al-Minia University, Egypt in Developmental Biology. In 2002, he was awarded his PhD in Developmental Molecular Biology (Molecular Embryology) by the University of Nottingham, Institute of Genetics, School of Medicine. After that he took up a Senior Research Associate position at the School of Biological Sciences, University of East Anglia, UK before joining CEGMR as an Associate Professor in 2012.
Prof. Abu-Elmagd’s research focuses on the study of gene expression and regulation during early embryonic development with the aim of understanding the molecular mechanisms which control early developmental events. To achieve this, Prof. Abu-Elmagd established the Functional and Developmental Genomics unit at CEGMR. In addition, Prof. Abu-Elmagd has extended his research to analyse the regulatory network and is particularly interested in those which govern embryonic development and play a dual role in regulating cancer and other human diseases. To achieve this, Prof. Abu-Elmagd uses in vivo and in vitro gain- and loss-of-function approaches and analyses his data using a wide range of advanced platforms available at CEGMR including microarray, sequencing, proteomics, flowcytometry and cellular imaging. In addition, Prof. Abu-Elmagd has a special interest in male infertility research and is working on establishing advanced molecular male infertility screening assays.
Prof. Abu-Elmagd has numerous scientific achievements which have been featured outstanding publications (http://www.ncbi.nlm.nih.gov/pubmed/?term=Abu-Elmagd+m). Organised by CEGMR, Prof. Abu-Elmagd led the scientific editorial board of the 2nd and 3rd International Genomic Medicine Conference (IGMC). Prof. Abu-Elmagd has established an open access journal (npj Genomic Medicine) in partnership with one of the world’s leading scientific publishers, Nature Publishing Group (NPG), and is an editor of this journal.
Kharrat N, Assidi M, Abu-Elmagd M, Pushparaj P, Alkhaldy A, Arfaoui L, Naseer M, El Omri A, Messaoudi S, Buhmeida A, Rebai A. (2019). Data mining analysis of human gut microbiota links Fusobacterium spp. with colorectal cancer onset. Bioinformation 15(6): 372-379.
Kalamegam G, Sait KHW, Ahmed F, Kadam R, Pushparaj PN, Anfinan N, Rasool M, Jamal MS, Abu-Elmagd M, Al-Qahtani M. (2018). Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis. Front Oncol. 7;8:592. doi: 10.3389/fonc.2018.00592.
- Abu-Elmagd M (2018). Use of chick neural tube for optimising the PSM and epithelial somites electroporation parameters: A detailed protocol. J Biol. Meth. (Accepted in 29th March, 2018) (In Press, DOI: 10.14440/jbm.%Y.253).
- Naseer MI, Alwasiyah MK, Abdulkareem AA, Bajammal RA, Trujillo C, Abu‑Elmagd M, Jafri MA, Chaudhary AG, Al‑Qahtani MH (2018). A novel homozygous mutation in SZT2 gene in Saudi family with developmental delay, macrocephaly and epilepsy. Genes & Genomics. 23rd February 2018. (Impact Factor: 1.566) (DOI: 10.1007/s13258-018-0673-5).
- Bahamat AA, Assidi M, Lary SA, Almughamsi MM, Peer Zada AA, Chaudhary A, Abuzenadah A, Abu-Elmagd M, Al-Qahtani M (2018). Use of array comparative genomic hybridization for the diagnosis of Digeorge syndrome in Saudi Arabian population. Cytog Genom Res. February 17, 2018. (Impact factor: 1.354) (DOI: 10.1159/000487094).
- Abu-Elmagd M, Joanna Mulvaney, Grant Wheeler. (2017). Frizzled-7 is required for Xenopus heart development. Biol Open. 2017 Nov 3. pii: bio.026963. (Impact factor: 2.50) (DOI: 10.1242/bio.026963)
- Abu-Elmagd M, Alghamdi MA, Shamy M, Khoder MI, Costa M, Assidi M, Kadam R, Alsehli H, Gari M, Pushparaj PN, Kalamegam G, Al-Qahtani MH. (2017). Evaluation of the effects of airborne particulate matter on Bone Marrow-Mesenchymal Stem Cells (BM-MSCs): Cellular, molecular and systems biological approaches. Int. J Environ Res Public Health. 20;14(4). pii: E440. (Impact factor: 2.101) (DOI: 10.3390/ijerph14040440).