تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
Brachytherapy Boost in the Neoadjuvant Radiation Therapy for Locally Advanced Rectal Cancer at King Abdulaziz University Hospital
Brachytherapy Boost in the Neoadjuvant Radiation Therapy for Locally Advanced Rectal Cancer at King Abdulaziz University Hospital
 
الموضوع : العلاج بالاشعاع 
لغة الوثيقة : الانجليزية 
المستخلص : The aim is to evaluate the pathological complete response and toxicity when using brachytherapy boost as part of the preoperative chemoradiation therapy in patients with rectal cancer. A retrospective review of all patients with rectal cancer treated at King Abdulaziz University Hospital. Fifty-five patients had neoadjuvat radiotherapy 45 Gy in 25 fractions of external beam radiation as Phase I of radiotherapy followed by external beam boost: 540 cGy/3 fractions in 31 patients or Ir192 HDR brachytherapy boost in 17 patients. The pathological response rate, toxicity profile, overall survival and disease free survival was compared between different radiation therapies modalities. The pathological response rate was complete in 14 (25.5%) patients, partial (PR) in 29 (52.7%) patients, unknown (did not do surgery) in 9 (16.5%) patients and stable disease in 3 (5.4%) patients. In brachytherapy boost, pathological complete response was 47% vs. 18% external beam boost (p = 0.004). Toxicity profile was better in the brachytherapy group. Overall survival was 93% and the disease free survival was 60% which were not influenced by the modality of radiation therapy used. High Dose Rate Brachytherapy boost result in a higher pathological response rate without increase in side effect as compared to the external beam radiation boost in the neoadjuvant radiation therapy for locally advanced rectal cancer 
ردمد : 1319-1004 
اسم الدورية : مجلة العلوم الطبية 
المجلد : 16 
العدد : 1 
سنة النشر : 1430 هـ
2009 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Monday, July 25, 2011 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
ياسر بهادرBahadur, Yasir باحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 29978.pdf pdf 

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