تفاصيل الوثيقة

نوع الوثيقة : مقال في مجلة دورية 
عنوان الوثيقة :
علاج الميلاتونين لمشاكل النوم لدى الأطفال .
Melatonin for the Treatment of Handicapped Children with Severe Sleep Disorder.
 
لغة الوثيقة : الانجليزية 
المستخلص : Sleep disorders are common in children with mental retardation and neurological disorders. Melatonin is a recently developed natural compound that has been used successfully in sleep disorders. Our objective is to report our experience with melatonin for the treatment of circadian rhythm sleep disorder in handicapped children. An open trial of melatonin in a group of handicapped children with severe sleep disorder was conducted prospectively. The circadian rhythm sleep disorder was persistent for at least 6 months and failed to respond to at least 1 hypnotic drug. Therapeutic response was recorded according to: 1) The average number of hours asleep per 24 hours, 2) The average number of awakening per night, 3) The average number of nights with delayed sleep onset, and 4) The average number of nights with early morning arousals. Ten consecutive children (4 males and 6 females) with ages ranging between 1-11 years (mean 5.4) were included. Nine children had documented mental retardation, which was severe in 6 (67%). The majority of children had epilepsy and visual impairment (70%). All children were followed for 4-12 months (mean 7.5) following the initiation of a 3 mg bedtime melatonin. The majority (80%) had a dramatic response to melatonin. One child had a history of persistent nocturnal enuresis, which completely resolved after initiating melatonin therapy. No side effects were reported. To conclude, melatonin is a well tolerated, safe, and very effective drug for the treatment of severe circadian rhythm sleep disorder in handicapped children. It has minimal side effects and is relatively inexpensive. Wider use of this drug is recommended. 
ردمد : 0940-5429 
اسم الدورية : Pediatric Neurology 
المجلد : 3 
العدد : 23 
سنة النشر : 2000 هـ
2000 م 
نوع المقالة : مقالة علمية 
تاريخ الاضافة على الموقع : Saturday, March 13, 2010 

الباحثون

اسم الباحث (عربي)اسم الباحث (انجليزي)نوع الباحثالمرتبة العلميةالبريد الالكتروني
محمد جانjan, Mohammed باحثدكتوراه 

الملفات

اسم الملفالنوعالوصف
 25938.doc doc 

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