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Faculty of Medicine
Document Details
Document Type
:
Article In Journal
Document Title
:
A matched case-control study of Triple negative vs. HER-2 positive (irrespective of hormonal status) breast cancer: two subtypes with high risk features and poor outcome
A matched case-control study of Triple negative vs. HER-2 positive (irrespective of hormonal status) breast cancer: two subtypes with high risk features and poor outcome
Subject
:
Oncology
Document Language
:
English
Abstract
:
Genetic profile studies of breast cancer identified a number of biologically different subtypes. These genetic subtypes are often surrogated by estrogen receptors (ER), progesterone receptors (PR) and HER2 status as measured by immunohistochemistry (IHC). Triple negative (TN) subtype is recognized to have high risk features and poor outcome. Over expression of the HER2 is also recognized as a poor outcome marker. The characteristics and outcome of HER2 positive tumours (irrespective of hormonal status) (HER2 HR+/-) identified by IHC have not addressed in the era of surrogate genetic subtyping. Therefore, we retrospectively compared the risk features and clinical outcome of patients with TN against these with HER2 HR+/- tumours
ISSN
:
2078-2101
Journal Name
:
The Gulf Journal of Oncology
Volume
:
7
Issue Number
:
1
Publishing Year
:
1431 AH
2010 AD
Article Type
:
Article
Added Date
:
Sunday, April 3, 2011
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
ياسر بهادر
Bahadur, Yasir
Researcher
Doctorate
Files
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Type
Description
29520.pdf
pdf
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