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Document Type |
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Article In Journal |
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Document Title |
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The diagnosis of "pathological hyperglycaemia' in gestational diabetes in a high risk obstetric population The diagnosis of "pathological hyperglycaemia' in gestational diabetes in a high risk obstetric population |
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Subject |
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Obstetrics and Gynecology |
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Document Language |
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English |
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Abstract |
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In order to define a level of "pathological hyperglycaemia', i.e. glucose intolerance that predicts perinatal morbidity among the obstetric population, 100 g glucose tolerance tests (GTTs) were performed in 660 patients attending for antenatal care at the University Hospital in Jeddah. The results were analysed in two ways: (1) patients were stratified according to the number of abnormal glucose values on the GTTs and (2) patients were placed into one of three groups according to the 100 g GTT diagnostic criteria, i.e. normal (non-GDM), abnormal with fasting blood glucose (FBG) > or = 5.8 mmol l-1 (GDM), and abnormal with FBG < 5.8 mmol l-1 (gestational induced hyperglycaemia, GIH). Although there was a stepwise association between fetal/maternal morbidity with increasing number of abnormal glucose values, no level of glucose intolerance could be defined as a threshold level for normal response. However, when stratified by FBG, GDM patients were significantly heavier (78.5 kg +/- SD 14.9), had a higher incidence of both macrosomia (27.5%) and operative delivery (25.3%) than the other two groups (14.7%, 14.3%, and 15.4%, 12.8% in the non-GDM and GIH, respectively). It is suggested that among patients with abnormal GTT results a FBG > or = 5.8 mmol l-1 identifies a threshold for true "pathological hyperglycaemia' |
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ISSN |
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0742-3071 |
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Journal Name |
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Diabetic Medicine |
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Volume |
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13 |
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Issue Number |
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10 |
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Publishing Year |
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1417 AH
1996 AD |
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Article Type |
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Article |
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Added Date |
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Saturday, April 2, 2011 |
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Researchers
| حسن نصرت | Nasrat, Hasan | Investigator | Doctorate | |
| محمد العرضاوي | Ardawi, Mohammed | Researcher | Doctorate | |
| بهاء أباالخيل | Abalkhail, Bahaa | Researcher | Doctorate | |
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