Document Details

Document Type : Article In Journal 
Document Title :
Delayed Effects of Acute Deltametrin Toxicity on Brain and Blood Monoamines and Free Amino –Acids: Therapeutic Role of Selenium-Supplementation
التأثير السمي المتأخر للدلتاميثرين علي الامينات في المخ والدم: التأثير العلاجي للسيلينيوم
 
Subject : toxicity and selenium 
Document Language : English 
Abstract : Abstract: The present study was designed to investigate the therapeutic effect of selenium on delayed deltamethrin (DM) neurotoxicity. Animals under investigation were treated with a single acute dose of deltamethrin (111.25 mg/100 g body weight). The therapeutic effect of selenium has been evaluated by administration of a daily dose either individually or in antioxidant preparation ( Antox) for a period of three weeks.Acute deltamethrin intoxication induced marked altrations in the brain and blood levels of monoamines and free amino acids as well as acetylcholinesterase activity. Selenium supplementation, either individually (DMS) or in antioxidant preparation (DMA), showed a considerable ability to attenuate some but not all signs of delayed deltamethrin neurotoxicity. Among the two Se-supplemented groups, it was difficult to see a clear therapeuMA showed the best results in others reflecting different mechanisms of action.These therapeutic effects seemed to be time dependent 
ISSN : 1819-3420 
Journal Name : Research Journal of Environmental Toxicology 
Volume : 2 
Issue Number : 1 
Publishing Year : 1429 AH
2008 AD 
Article Type : Article 
Added Date : Monday, December 27, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
سيد محمد راويRawi, Sayed MohamedInvestigatorDoctoraterawisayed@yahoo.com

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