Document Details
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Document Type |
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Article In Journal |
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Document Title |
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Synthesis and antimicrobial evaluation of some 1,3-thiazole, 1,3,4-thiadiazole, 1,2,4-triazole, and 1,2,4-triazolo[3,4-b][1,3,4]thiadiazine derivatives including a 5-(benzofuran-2-yl)-1-phenylpyrazole moiety. تشييد مركبات جديدة محتوية على البنزوفيران و البيرازول كمضادات للميكروبات |
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Subject |
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Organic Chemistry |
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Document Language |
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English |
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Abstract |
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Potassium hydrazinecarbodithioate was prepd. by treatment of acid hydrazides with carbon disulfide in the presence of potassium hydroxide. Reaction of this potassium salt with hydrazine hydrate, phenacyl bromide, or hydrazonoyl chlorides afforded 1,2,4-triazoles, 1,3-thiazoles, and 1,3,4-thiadiazoles. Reaction of the 1,2,4-triazole deriv. with phenacyl bromide or hydrazonoyl chlorides afforded the corresponding 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines. All these new compds. were screened for antibacterial and antifungal activity. Some had promising activity. |
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ISSN |
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0026-9247 |
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Journal Name |
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Monatshefte fuer Chemie |
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Volume |
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140 |
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Issue Number |
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6 |
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Publishing Year |
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1430 AH
2009 AD |
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Article Type |
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Article |
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Added Date |
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Saturday, December 25, 2010 |
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Researchers
| بكر فتحى عبد الوهاب | Abdel-Wahab, Bakr Fathi | Researcher | Doctorate | |
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