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Document Details
Document Type
:
Article In Journal
Document Title
:
Influence of Retinal Extracts and Fibroblast Growth Factor on Lentoidogenesis in the Chick EmbryoRetinal Glial Cell Cultures
ثأثير مستخلصات الشبكية وعامل نمو الخلايا الليفية على تكوين العديسات في زراعات الخلايا الغروية لشبكية أجنة الدجاج
Subject
:
Zoology
Document Language
:
English
Abstract
:
Extract prepared from embryonic chick retina stimulate~ growth and particularly lentoidogenesis when added as a supplement to retinal glial (RG) cultures in vitro. This effect is especially marked when using a medium (H) containing 5% horse serum, where growth factors are likely to be limiting. The number of lentoids in such cultures increases with the concentration of extract. Using extracts from earlier and later stages of retinal development, there is an age-dependent decline in the extent to which lentoidogenesis is stimulated. .t is suggested that these efforts are mediated by growth fa~ors present in the retinal extract acting upon Muller glial cells or their precursors in the RG cultures. In support of this suggestion, we show that purified fibroblast growth factor (but not epidermal growth factor) exerts similar effects on 8-crystalline in accumulation and number of lentoids.
ISSN
:
1012-1319
Journal Name
:
Science Journal
Volume
:
7
Issue Number
:
1
Publishing Year
:
1415 AH
1995 AD
Number Of Pages
:
8
Article Type
:
Article
Added Date
:
Sunday, October 11, 2009
Researchers
Researcher Name (Arabic)
Researcher Name (English)
Researcher Type
Dr Grade
Email
صالح عبدالعزيز كريم
S. A. KARIM
Researcher
فاطمة محمد سعد القدسي
F. M. AL-KUDSI
Researcher
ديفيد دي بوميرا
D. I. DE POMERA
Researcher
Files
File Name
Type
Description
22591.pdf
pdf
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