جامعة الملك عبدالعزيز

KING ABDULAZIZ UNIVERSITY

Center of Excellence In Genomic Medicine Research

Dr. Hans-Juergen Schulten

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Dr. Hans-Juergen Schulten

Coordinator of Microarray (Affymetrix) Service Unit
Assistant of Microarray (Agilent) Service Unit
Cancer Genomics & Genomic Screening Research Groups

Dr Schulten studied biology from 1989 to 1994 with the major in microbiology and the minor in biochemistry and ecology at the Technical University of Braunschweig, Germany. His diploma thesis focused on chitin-decomposing bacterial populations in different soils in an ecosystem network. From 1995 to 1998 he performed his doctoral study at the Institute of Human Genetics, University of Goettingen, Germany. In his doctoral thesis he worked on the transcriptional and translational regulation of the developmental proacrosin gene by in vitro and in vivo studies. From 1999 to 2007 he worked as a postdoc at the Gastroenteropathology Department of the University of Goettingen in the field of molecular cytogenetics. Subsequent to a short employment at the University of Toledo, OH, Dr. Schulten joined the CEGMR in 2009 where he is working in the field of tumor biology and supervises the Affymetrix Microarray Service Unit.

Funded and accepted KACST Projects:
1. Funded project AT-32-98: Molecular genetic profiling of brain tumors.
2. Accepted project 13-MED2337-03: Molecular genetic profiling of lung cancer by state-of-the-art technology.
3. Accepted project 13-BIO2289-03: Advanced molecular genetic analysis in proliferative thyroid lesions.


Selected Publications:
1. Effect of BRAF mutational status on expression profiles in conventional papillary thyroid carcinomas
Schulten HJ, Alotibi R, Al-Ahmadi A, Ata M, Karim S, Huwait E, Gari M, Al-Ghamdi K, Al-Mashat F, Al-Hamour O, Al-Qahtani M, Al-Maghrabi J
BMC Genomics 2015, 16(Suppl 1):S6.

2. Comparison of microarray expression profiles between follicular variant of papillary thyroid carcinomas and follicular adenomas of the thyroid
Schulten HJ, Al-Mansouri Z, Baghallab I, Bagatian N, Subhi O, Karim S, Al-Aradati H, Al-Mutawa A, Johary A, Meccawy AA, Al-Ghamdi K, Al-Hamour O, Al-Qahtani M, Al-Maghrabi J.
BMC Genomics 2015, 16(Suppl 1):S7.

3. Comprehensive survey of HRAS, KRAS, and NRAS mutations in proliferative thyroid lesions from an ethnically diverse population
Schulten HJ, Salama S, Al-Ahmadi A, Al-Mansouri Z, Mirza Z, Al-Ghamdi K, Al-Hamour OA, Huwait E, Gari M, Al-Qahtani MH, Al-Maghrabi J.
Anticancer Res. 2013;33:4779-84.

4. Mutational screening of RET, HRAS, KRAS, NRAS, BRAF, AKT1, and CTNNB1 in medullary thyroid carcinoma. Anticancer Res.
Schulten HJ, Al-Maghrabi J, Al-Ghamdi K, Salama S, Al-Muhayawi S, Chaudhary A, Hamour O, Abuzenadah A, Gari M, Al-Qahtani M.
2011;31:4179-83.             
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