Dr. Shakeel Ahmad Ansari
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Dr. Shakeel Ahmed Ansari

Assistant of Proteomics Service Unit
Pharmacogenomics Research Group

Dr. Ansari joined Center of Excellence in Genomic and Medicine Research as an Assistant Professor in 2011. His doctoral research was focused on comparative studies of soluble and immobilized β galactosidases and their optimization in relation to various physico-chemical parameters for large scale production of lactose-free dairy products. Currently, Dr. Ansari is developing techniques for the rational synthesis of functional nanomaterials for applications in enzyme immobilization, drug delivery systems and construction of biosensors. His research work centers around manipulating the surface of nanomaterials to elicit control over protein adsorption as well as cell adhesion, orientation and function, in order to obtain an efficient and controlled “nanoparticle based drug delivery systems” for treating various biological disorders. Moreover, he is involved in “Proteomics Service Unit” to provide state of art proteomics research and services to researchers and private companies in Kingdom of Saudi Arabia.

Funded Projects in KACST (2 million SAR):
1. (As a PI) Surface functionalization of nanodiamonds and their potential application in herceptin targeted drug delivery (12-NAN3097-03R).
2. (As a Co-I) Role of START domains in mediating cholesterol transport to the site of hormone biosynthesis in aging process (13-MED293-03).

Selected Publications:
1. Potential application of enzymes immobilized on/in nano materials: A review.
Shakeel Ahmed Ansari and Qayyum Husain.
Biotechnology Advances [http://www.ncbi.nlm.nih.gov/pubmed/21963605].

2. Cost effective surface functionalization of silver nanoparticles for high yield immobilization of Aspergillus oryzae β galactosidase and its application in lactose hydrolysis
Shakeel Ahmed Ansari, Rukhsana Satar, Fahad Alam, Mohammed Husein Al-Qahtani, Adeel Gulzar Chaudhary, Muhammad Imran Naseer, Sajjad Karim, Ishfaq Ahmed Sheikh
Process Biochemistry [http://www.sciencedirect.com/science/article/pii/S1359511312003716].

3. Down regulation of Dopamine D1 receptors and increased neuronal apoptosis upon ethanol and PTZ exposure in prenatal rat cortical and hippocampal neurons
Muhammad Imran Naseer, Ikram Ullah, Mahmood Rasool, Shakeel Ahmed Ansari, Ishfaq Ahmed Sheikh, Fahmida Bibi, Adeel Gulzar Chudhary, Mohammed Hussein Al-Qahtani.
Neurological Sciences [http://www.ncbi.nlm.nih.gov/pubmed/24810836].

4. Protective effect of Solanum nigrum leaf extract on immobilization stress induced changes in rat brain.
Syed Kashif Zaidi, Md Nasrul Hoda, Shams Tabrez, Shakeel Ahmed Ansari, Naheed Banu, Shririn Hassan, Mohammed Hussein Al Qahtani, Mohd Shahnawaz Khan
Evidence Based Complementary and Alternative Medicine [http://www.hindawi.com/journals/ecam/2014/912450/].

5. Nanoparticle-based therapy in genomics
Mahmood Rasool, Arif Malik, Abdul Manan, Shakeel Ahmed Ansari, Muhammad Imran Naseer, Mohammad Qazi, Mohd Asif, Siu Wei Gan, Mohammad Amjad Kamal
Current Drug Metabolism [http://www.ncbi.nlm.nih.gov/pubmed/25495736].
Last Update
1/6/2016 9:55:00 AM